A new peptide antibiotic KM-8.

A new peptide antibiotic KM-8.

In the course of screening for new antibiotics, a strain of a new species belonging to Streptoverticillium was found to produce a new peptide antibiotic. Most of the procedure used in the taxonomic study of the strain were carried out in accordance with the method adopted by the International Streptomyces Project (ISP)1) Additional media recommended by WAKSMAN2,3) were also used. From the morph...

A new antibiotic KM-214 produced by a strain of Bacillus.

8-Methoxygriseorhodin C, a new member of griseorhodin antibiotic.

was isolated from a soil sample collected in Jiangsu Province, People's Republic of China. In this communication, we would like to report the production, isolation and structural elucidation of 8-methoxygriseorhodin C. The producing strain was inoculated in a 500-ml baffled Erlenmeyer flask containing 1 10 ml medium consisting of glycerol 2.0%, soybean meal 1.5%, CoCl3-6H2O 0.0005% and K2HPO4 0...

Minimycin, a new antibiotic.

During the course of our screening program for new antibiotics, Streptomyces sp. 80432 isolated from a soil sample was found to produce a water-soluble antibiotic. This antibiotic, named minimycin, showed not only inhibitory activity against Grampositive and Gram-negative bacteria, but also antitumor activity. Isolation and purification by a chromatography gave a colorless crystalline substance...

Viridenomycin, a new antibiotic.

Viridenomycin, a new crystalline antibiotic, was isolated from the culture broth of Streptomyces viridochromogenes strain No. T-24146. Viridenomycin is a weakly acidic and lipophilic substance, which exhibits a strong absorption maximum at 310 nm and shows strong activity against Trichomonas vaginalis and gram-positive bacteria.